The possible connection between hypertension and endodontic variables has been analysed. A cross-sectional study carried out in Spain to determine the prevalence of apical periodontitis and RCT in hypertensive patients and control subjects concluded that no association existed between hypertension and endodontic variables (Segura-Egea et al. 2010).
However, Mindiola et al. (2006) and Wang et al. (2011) reported an increased loss of root canal filled teeth in hypertensive patients.
A cross-sectional study was conducted to determine the prevalence of apical periodontitis and RCT in post-menopausal women with osteoporosis (Lo pez-Lo pez et al. 2013).
Bone mineral density (BMD) of 75 post-menopausal women was measured using dual-energy X-ray absorptiometry. Three BMD groups were established (27 healthy bone group, 36 osteopenics and 12 osteo- porotics), and periapical and endodontic status were assessed using digital panoramic radiographs and the PAI system (Ørstavik et al. 1986).
The results demonstrated that the prevalence of apical periodontitis was marginally associated with BMD.
Inherited coagulation disorders
A cross-sectional study investigated the prevalence of endodontic variables in 58 patients with inherited coagulation disorders, such as haemophilia A or B, or von Willebrand disease, compared to 58 healthy controls (Castellanos-Cosano et al. 2013a).
Results revealed that patients with inherited coagulation disorders had significantly more teeth with apical periodontitis.
Chronic liver disease
The prevalence of apical periodontitis and RCT in a group of 42 patients with chronic liver disease, candidates for liver transplant, compared to 42 healthy controls, has been also studied (Castellanos-Cosano et al. 2013b).
Results revealed a higher prevalence of apical periodontitis and RCT in these patients, compared to healthy controls.
In conclusion, those disorders may be the relationship with endodontic variables. Such findings will surely have important implications in terms of the therapeutic approaches in these patients.